question #2 Sahih al-Bukhari 3432, Book 60, Hadith 103 : What significance do Mary, the daughter of Imran, and Khadija hold in Islamic history?

I heard the Prophet (ﷺ) saying, “Mary, the daughter of `Imran, was the best among the women (of the
world of her time) and Khadija is the best amongst the women. (of this nation).